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Added: 20 July 2008
Updated: 31 July 2008
Expires: 16 January 2009
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| Full Name: |
Dr. Afsaneh Motamed-Khorasani |
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| Position Sought: |
IVF Lab Director or Senior Embryologist/Research Scientist |
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| Primary
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| Address: |
Toronto ON Canada M4S 1V5 |
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| E-mail
Address: |
Contact Afsaneh |
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| English, Persian |
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Tel: 416-454-5589 115 Soudan Ave. AfsanehMotamed@yahoo.com Toronto, ON M4S 1V5
HIGHLIGHTS of EXPERTISE
- Twelve years of hands-on experience in ART and a wide variety of molecular biology techniques: - Protein interaction assay, Affymetrix, cDNA/Tissue Microarray, database Analysis/bioinformatics - Primary/secondary tissue culture (human in vitro fertilization, neuronal/cancer cells), Cloning, and transfection - Northern, Southern, and Western blotting, real-time PCR and related analysis software -.Monoclonal antibodies and FACS Analysis/Flow Cytometry, Immunohistochemistry, and assay development
- Seven years of experience/practice in clinical setting
- Proven ability to work effectively as part of a multidisciplinary research team
- Proven scientific/technical writing, teaching, and supervisory skills
- Understanding/experience in GLP and GMP environment
- High level of competencies in interpersonal skills, project management, negotiation/conflict resolution
- Well-organized, detail-oriented, tenacious, and proactive
EDUCATION Ph.D. (Reproductive Endocrinology, Cancer Research) U of T, Dept. of physiology, Faculty of Medicine, Toronto, ON M.Sc. (Reproductive Physiology) UBC, Dept. of Obstetrics and Gynecology, Dept. of Animal Sci., Faculty of Medicine, Vancouver, BC B.Sc. (Obstetrics) Shahid Beheshti University of Medical Sciences, Tehran, Iran Jan. 2001-Jan. 2006 Sep. 1997-Sep. 1999 Sep. 1988-Dec. 1992 EMPLOYMENT HISTORY Microbix Biosystems Inc.
* Acted as Senior research scientist in the R&D department, developed and optimized different assays
* Established an IVF lab and brought it to the level of being fully operational with greater than 80% cleavage rate
* Developed different proposals and took them to the stage of being fully optimized/operational
* Practiced in GLP/GMP environment
* Developed SOPs for assay development followed by methodology optimization Queen’s College, Mississauga, ON, Lecturer/Instructor
- Instructed, college/high school students in the subjects of Biology, Molecular Biology, Genetics, Physiology, Anatomy, Health, English The University of Toronto, Toronto, ON, Scientific Patent Advisor/Research Scientist
- Technical Advisor for Technology Transfer Department
- Searched scientific Patent database, drafted, filed, and executed patent applications
- Utilized a wide variety of molecular biology techniques to maximize the project efficiency
- Created and managed databases for the high throughput studies at hand for data mining The University of British Columbia, Vancouver, B.C., Research Scientist
- Participated in a variety of technical duties involved in human/bovine IVF Lab procedures to include, but not limited to, assisting with oocyte retrievals, insemination and embryo transfers, freezing sperm/oocyte/embryo
- Published two scientific papers as a results of my work in the lab
- Managed the lab activities including experimental design, experiments, data collection and analysis, trouble shooting, collaborations, reports/manuscripts, and publication Dr. Bahonar Medical Clinic, Tehran, Iran, Obstetrician/Family Practitioner
- Established my own clinic to visit Obstetric patients
- Administered medication, birth control pills, IUDs for obstetric patients based on their conditions
- Assisted pregnant women in natural deliveries and administered post-partum care and provided neonatal care, vaccination, family planning, and consulting for patient families Aug. 2007-Present Mar. 2007-Aug. 2007 Sep. 2000-Apr 2007 Sep. 1996- Aug. 2000 Sep. 1993-Aug. 1996 TRAINING AND DEVELOPMENT NIH On-Line Technology Transfer Training, Toronto, ON, Canada, May 27, 2007. IPIC Patent Agent Training Course (4-month course), IPIC, Toronto, ON, Canada, 2006. Certificate in Introduction to Intellectual Property (5-day course), McGill University, ON, Canada, 2006. Certificate in Teaching Higher Education (THE500H1), The University of Toronto, ON, Canada, 2004. Course in Proteomics and Functional Genomics (JTB2010H), The University of Toronto, ON, Canada, 2003. Certificate in Statistical Learning & Data Mining, Georgetown University, Washington DC, USA, 2002. Certificate of Instructional Skills Workshop, UBC Faculty Development Program, Vancouver, BC, Canada, 1999. Permanent Permit of Professional Clinical Practice, Ministry of Health, Treatment and Medical Education, Tehran, Iran, 1996. ABSTRACTS AND PUBLICATIONS Differentially Androgen-Modulated Genes in Ovarian Epithelial Cells from BRCA1 Mutation Carriers and Control Patients Predict Ovarian Cancer Survival and Disease Progression. Motamed-Khorasani A, Jurisica I, Letarte M, Shaw PA, Parkes RK, Zhang X, Evangelou A, Rosen B, Murphy KJ, Brown TJ. Oncogene, July 10, 2006, doi: 10.1038/sj.onc.1209773. Androgen-Altered Gene Expression Profiles in Ovarian Epithelial Cells from BRCA1 and 2 Mutation Carriers as Compared to Cells from Control Patients. Conjoint Annual Meeting of the American Society for Reproductive Medicine and the Canadian Fertility and Andrology Society, ASRM/CFAS, Montreal, Quebec, Canada, October 2005. Integrated Analysis of Androgen-Altered Genes in Epithelial Ovarian Cancer Using a Predicted Human Protein-Protein Interaction Network. 95th American Association of Cancer Res. annual meeting, Orlando, Florida, USA, 2004. Comparative Expression Profiles of Androgen-Responsive Genes in Malignant/Non-Malignant Ovarian Cells. HUPO 2nd Annual World Congress, annual meeting, Montreal, Canada, 2003. Androgen Treatment Effects in Malignant/Non-Malignant Ovarian Epithelial Cells. Annual meeting for the Dept. of Physiol. Res. Day/Frontiers in Physiology, University of Toronto, Toronto, Canada, 2002. Mechanism of Cholesterol Inhibition on Progesterone-Induced Acrosome Reaction of Human Sperm. Motamed-Khorasani A, Lee CYG, Cheung AP. Journal of Andrology, July/Aug., 2000, 21(4). Progesterone and GnRH Surface Receptors in Human Spermatozoa, Motamed-Khorasani A, Lee CYG, 2000. Effects of Progesterone and Cholesterol on Bovine In Vitro Fertilization. Motamed-Khorasani A, Lee CYG, 1999 Chinese Canadian Academic & Professional Society annual meeting, Vancouver, BC, Canada, 1999. Progesterone and Cholesterol Effect on In Vitro Embryo Production in Dairy Cattle. Motamed-Khorasani A, Lee CYG, 32nd annual Meeting of Society of Reproduction, Washington State University, Pullman, Washington, USA, 1999. Effects of Progesterone and Cholesterol on Capacitation and Acrosome Reaction of Bovine Sperm. Motamed-Khorasani A, Rajamahendran R, Lee CYG, 32nd annual Meeting of Society of Reproduction, Washington State University, Pullman, Washington, USA, 1999. Pre-Treatment of Sperm with Progesterone & Cholesterol & Its Effect on In Vitro Embryo Production in Cattle. Motamed-Khorasani A, Rajamahendran R, Lee CYG, 25th Annual Conference of International Embryo Transfer Society; Quebec City, Canada, 1999. Mechanism of Natural and Induced Apoptosis in Human and Mice Testis. Motamed-Khorasani A, Rajamahendran R, Lee CYG, UBC, Vancouver, BC, Canada, 1999. Assessment of Progesterone-Induced Acrosome Reaction by Biotinylated Monoclonal Antibody Probes. Lee CYG, Motamed-Khorasani A, Dorjee S. The American Journal of Reproductive Immunology, 1998; 39:16. Mechanism of Cholesterol Inhibition on Progesterone-Induced Acrosome Reaction of Human Sperm. Motamed-Khorasani A, Lee CYG, 16th World Congress on Fertility & Sterility, San Francisco, California, USA, 1998. Developmental Competence of Bovine Oocytes Matured In Vitro in Various Environments. Motamed-Khorasani A, Rajamahendran R, Lee CYG, 78th Canadian Society of Animal Sci. Annual Conf. (CSAS), University of BC, Vancouver, BC, Canada, 1998. Assessment of Progesterone-Induced Acrosome Reaction by Biotinylated Monoclonal Antibody Probes. Motamed-Khorasani A, Lee CYG, 78th Canadian Society of Animal Sci. Annual Conf. (CSAS), University of BC, Vancouver, BC, Canada, 1998. New Advances in Sexing Sperm, Motamed-Khorasani A, UBC, Vancouver, BC, Canada, 1997. AWARDS/SCHOLARSHIPS Department of Physiology Fellowship, University of Toronto, Dept. of Physiology Kristi Piia Callum Memorial Fellowship in Ovarian Cancer, University of Toronto, Faculty of Medicine Dept. of Physiology Scholarship, University of Toronto, Dept. of Physiology Graduate Student Fellowship, University of British Columbia, Dept. of Obstetrics & Gynecology Project Assistantship, University of British Columbia, Dept. of Medical Genetics Graduate Research Assistantship, University of British Columbia, Dept. of Obstetrics & Gynecology 2004-2006 2003-2004 2000-2003 1999-2000 1998-1999 1997-1999 TEACHING EXPERIENCE Instructed high school/College students (Biology, Health Sciences) Queen’s College, Mississauga, ON, Canada Performed teaching assistantship for a graduate course in reproductive physiology The University of British Columbia, Vancouver, BC, Canada Taught several undergraduate/graduate student the lab techniques in the field of molecular biology The University of Toronto, Toronto, ON, Canada Mar. 2007-Present 1999-2000 1997-2006 Extracurricular ACTIVITIES Invited Speaker at Heart and Stroke Foundation of Ontario Seminar, Toronto, ON. Community Representative, Art History Representative, Toronto, ON. Founder/President/Directing manager, U of T Student Choir Group, the University of Toronto, Toronto, ON. Fund Raiser/Choir Singer, U of T Student Choir Group, the University of Toronto, Toronto, ON. Volunteer Administrative Assistant, Immigration Services Society, Vancouver, BC. Supervisor (1-week project of up-rooting polio in Iran), Shemiranat Health Center, Tehran, Iran. May 27, 2007 Jul. 15, 2005 Feb. 2004-Present Feb. 2004-Present Sep. 1996-Jan. 1997 Aug. 15-18, 1994 References Available upon Request
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| Career History: |
EMPLOYMENT HISTORY
Microbix Biosystems Inc
* Acted as Senior research scientist in the R&D department, developed and optimized different assays
* Established an IVF lab and brought it to the level of being fully operational with greater than 80% cleavage rate
* Developed different proposals and took them to the stage of being fully optimized/operational
* Practiced in GLP/GMP environment
* Developed SOPs for assay development followed by methodology optimization
Queen’s College, Mississauga, ON, Lecturer/Instructor
• Instructed, college/high school students in the subjects of Biology, Molecular Biology, Genetics, Physiology, Anatomy, Health, English
The University of Toronto, Toronto, ON, Scientific Patent Advisor/Research Scientist
• Technical Advisor for Technology Transfer Department
• Searched scientific Patent database, drafted, filed, and executed patent applications
• Utilized a wide variety of molecular biology techniques to maximize the project efficiency
• Created and managed databases for the high throughput studies at hand for data mining
The University of British Columbia, Vancouver, B.C., Research Scientist
• Participated in a variety of technical duties involved in human/bovine IVF Lab procedures to include, but not limited to, assisting with oocyte retrievals, insemination and embryo transfers, freezing sperm/oocyte/embryo
• Published two scientific papers as a results of my work in the lab
• Managed the lab activities including experimental design, experiments, data collection and analysis, trouble shooting, collaborations, reports/manuscripts, and publication
Dr. Bahonar Medical Clinic, Tehran, Iran, Obstetrician/Family Practitioner
• Established my own clinic to visit Obstetric patients
• Administered medication, birth control pills, IUDs for obstetric patients based on their conditions
• Assisted pregnant women in natural deliveries and administered post-partum care and provided neonatal care, vaccination, family planning, and consulting for patient families
Aug. 2007-Present
Mar. 2007-Aug. 2007
Sep. 2000-Apr 2007
Sep. 1996- Aug. 2000
Sep. 1993-Aug. 1996 |
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| Experience: |
TRAINING AND DEVELOPMENT
NIH On-Line Technology Transfer Training
Toronto, ON, Canada, May 27, 2007
IPIC Patent Agent Training Course
IPIC, Toronto, ON, Canada, 2006
Certificate in Introduction to Intellectual Property
McGill University, Montreal, ON, Canada, 2006
Certificate in Teaching Higher Education (THE500H1)
The University of Toronto, Toronto, ON, Canada, 2004
Course in Proteomics and Functional Genomics (JTB2010H)
The University of Toronto, Toronto, ON, Canada, 2003
Course in Labeling and Hybridization of Microarray Chips
The Microarray Center Clinical Genomics Center, Toronto, ON, Canada, 2002
Certificate in Statistical Learning & Data Mining
Georgetown University, Washington DC, USA, 2002
Certificate of Instructional Skills Workshop
UBC Faculty Development Program, Vancouver, BC, Canada, 1999
Permanent Permit of Professional Clinical Practice
Ministry of Health, Treatment and Medical Education, Tehran, Iran, 1996
Certificate of Professional clinical Practice
Manzarieh Medical Clinic, Tehran, Iran, 1995
Certificate in Computer Turbo C Programming
Micro-system Education Center, Tehran, Iran, 1995
Certificate in Computer Operating and Basic Programming
Technical and Vocational Skills Training Center #13, Tehran, Iran, 1994 |
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| Education: |
Education
Doctor of Philosophy
Physiology (Reproductive Endocrinology/Cancer Research)
Department of Physiology, Faculty of Medicine
The University of Toronto
2001 - 2006
Master of Science
Reproductive Physiology
Department of Obstetrics and Gynecology, Faculty of Medicine
The University of British Columbia
1997 - 1999
Bachelor of Science
Obstetrics
Department of Obstetrics, Faculty of Medicine
Medical University of Shahid Beheshti
1988 - 1992 |
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| Personal details: |
Professional Memberships
Persian-Canadian Biomedical Scientists (PCBMS)
2005 - Present
Intellectual Property Institute of Canada (IPIC)
2005 - Present
Toronto Biotechnology Initiative (TBI)
2005 - Present
Endocrine Society
2004 - Present |
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| Interests and Hobbies: |
Extracurricular Activities
Invited Speaker
Heart and Stroke Foundation of Ontario May 2007 Seminar, Toronto, ON
May 27, 2007
Community Representative
Art History Representative, Toronto, ON
Jul. 15, 2005
Founder/President/Directing manager
University of Toronto Choir Group, The University of Toronto, Toronto, ON
Feb. 2004 - Present
Fund Raiser/Choir Singer
University of Toronto Choir Group, The University of Toronto, Toronto, ON
Feb. 2004 - Present
Volunteer Administrative Assistant
Immigration Services Society, Vancouver, BC
Sep. 1996 - Jan. 1997
Supervisor (1-week project of up-rooting polio in Iran)
Shemiranat Health Center, Tehran, Iran
Aug. 15, 1994 – Aug. 18, 1994 |
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| Further Information: |
AWARDS/SCHOLARSHIPS
Department of Physiology Fellowship ($5,000)
Faculty of Medicine, Dept. of Physiology, The University of Toronto
2004 - 2006
Kristi Piia Callum Memorial Fellowship in Ovarian Cancer ($8,000)
Faculty of Medicine, Dept. of Physiology, The University of Toronto
2003 - 2004
Dept. of Physiology Stipend ($67,000)
Faculty of Medicine, Dept. of Physiology, The University of Toronto
2001 - 2006
Dept. of Physiology Scholarship ($49,500)
Faculty of Medicine, Dept. of Physiology, The University of Toronto
2001 - 2004
Graduate Student Fellowship ($2,500)
Faculty of Medicine, Dept. of Obstetrics & Gynecology, The University of British Columbia
1999 - 2000
Project Assistantship ($4,500)
Faculty of Medicine, Dept. of Medical Genetics, University of British Columbia
1998 - 1999
Graduate Research Assistantship ($54,000)
Faculty of Medicine, Dept. of Obstetrics & Gynecology, University of British Columbia
1997 - 2000
Teaching Assistantship ($1,500)
Faculty of Medicine, Dept. of Animal Sciences, University of British Columbia
1999 – 2000 |
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| Publications: |
Research Abstracts and Presentations.
Altered TGF-β Signaling by FLJ12604 in Ovarian Cancer Cells. P. Shathasivam, A. Motamed-Khorasani, J. Wrana, K. Brown, I. Jurisica, T. Brown. 24th Annual Research Day, Department of Physiology, Faculty of Medicine, The University of Toronto, May 4, 2007.
Androgen-Altered Gene Expression Profiles in Ovarian Epithelial Cells from BRCA1 and 2 Mutation Carriers as Compared to Cells from Control Patients. Conjoint Annual Meeting of the American Society for Reproductive Medicine and the Canadian Fertility and Andrology Society, ASRM/CFAS, Montreal, Quebec, Canada, October 2005.
Integrated Analysis of Androgen-Altered Genes in Epithelial Ovarian Cancer Using a Predicted Human Protein-Protein Interaction Network. 95th American Association of Cancer Res. annual meeting, Orlando, Florida, USA, 2004.
Comparative Expression Profiles of Androgen-Responsive Genes in Malignant/Non-Malignant Ovarian Cells. HUPO 2nd Annual World Congress, annual meeting, Montreal, Canada, 2003.
Androgen Treatment Effects in Malignant/Non-Malignant Ovarian Epithelial Cells. Annual meeting for the Dept. of Physiol. Res. Day/Frontiers in Physiology, University of Toronto, Toronto, Canada, 2002.
Progesterone and GnRH Surface Receptors in Human Spermatozoa, Motamed-Khorasani A, Lee CYG, 2000.
Effects of Progesterone and Cholesterol on Bovine In Vitro Fertilization. Motamed-Khorasani A, Lee CYG, 1999 Chinese Canadian Academic & Professional Society annual meeting, Vancouver, BC, Canada, 1999.
Progesterone and Cholesterol Effect on In Vitro Embryo Production in Dairy Cattle. Motamed-Khorasani A, Lee CYG, 32nd annual Meeting of Society of Reproduction, Washington State University, Pullman, Washington, USA, 1999.
Effects of Progesterone and Cholesterol on Capacitation and Acrosome Reaction of Bovine Sperm. Motamed-Khorasani A, Rajamahendran R, Lee CYG, 32nd annual Meeting of Society of Reproduction, Washington State University, Pullman, Washington, USA, 1999.
Pre-Treatment of Sperm with Progesterone & Cholesterol & Its Effect on In Vitro Embryo Production in Cattle. Motamed-Khorasani A, Rajamahendran R, Lee CYG, 25th Annual Conference of International Embryo Transfer Society; Quebec City, Canada, 1999.
Mechanism of Natural and Induced Apoptosis in Human and Mice Testis. Motamed-Khorasani A, Rajamahendran R, Lee CYG, UBC, Vancouver, BC, Canada, 1999.
Assessment of Progesterone-Induced Acrosome Reaction by Biotinylated Monoclonal Antibody Probes. Lee CYG, Motamed-Khorasani A, Dorjee S. The American Journal of Reproductive Immunology, 1998; 39:16.
Mechanism of Cholesterol Inhibition on Progesterone-Induced Acrosome Reaction of Human Sperm. Motamed-Khorasani A, Lee CYG, 16th World Congress on Fertility & Sterility, San Francisco, California, USA, 1998.
Developmental Competence of Bovine Oocytes Matured In Vitro in Various Environments. Motamed-Khorasani A, Rajamahendran R, Lee CYG, 78th Canadian Society of Animal Sci. Annual Conf. (CSAS), University of BC, Vancouver, BC, Canada, 1998.
Assessment of Progesterone-Induced Acrosome Reaction by Biotinylated Monoclonal Antibody Probes. Motamed-Khorasani A, Lee CYG, 78th Canadian Society of Animal Sci. Annual Conf. (CSAS), University of BC, Vancouver, BC, Canada, 1998.
New Advances in Sexing Sperm, Motamed-Khorasani A, UBC, Vancouver, BC, Canada, 1997. |
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| Presentations: |
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