According to OECD Guidelines for Testing of Chemicals, Test No. 473, the in vitro chromosomal aberration test is used to evaluate the structural abnormalities of chromosome or chromatid, which involve intra-changes, inter-changes, deletions, breaks, fragments and chromosomal disintegration in metaphase stage of cell division.
STEMart provides in vitro chromosomal aberration test to assess the capacity of a medical device to induce structural chromosomal aberration of mammalian cells. This assay is available under either GLP (Good Laboratory Practice) or Non-GLP conditions.